We back the researchers most of the country hasn't found yet.
Proto Axiom’s active portfolio spans 11 biotech companies, including 3 clinical-stage companies, sourced from the same institutions that send researchers to Challenger Summit each year.
Challenger Summit is Australia's largest pitch day in life sciences. Every year, researchers, founders and clinical leads pitch for capital, mentorship and a path to patient impact — co-hosted by Proto Axiom and St Vincent's Curran Foundation.
Why pitch
Challenger Summit was built by Proto Axiom — Australia's biotech company-creation platform — to surface translational science before it ever reaches the conventional capital stack. The prize is the on-ramp. What happens after is the point.
Proto Axiom’s active portfolio spans 11 biotech companies, including 3 clinical-stage companies, sourced from the same institutions that send researchers to Challenger Summit each year.
A$250K to A$500K, depending on stream — awarded as a grant. No equity, no covenants attached to the prize itself.
Winners gain working access to Proto Axiom's clinical, regulatory, IP, finance and governance team — the same team supporting the portfolio.
Where the science fits, finalists enter a structured conversation with Proto Axiom about company formation and first round.
Intros to Proto Axiom's investor and clinical network — TIME Ventures, Catalio Capital, Reliance Life Sciences and a 33-strong private investor base.
Two streams · one stage
By combining the Proto Axiom Challenger Summit stream and the St Vincent's Discovery & Innovation 'Pitch for Health' grants into a single national showcase, we amplify visibility, foster collaboration, and streamline pathways to capital and commercialisation.
Our flagship stream. Open to researchers and founders from any Australian university, medical research institute or hospital — and to pre-seed / seed-stage Australian-incorporated companies. Ideal for translational programs ready for de-risking capital and a credible commercial framing.
Run in partnership with St Vincent's Curran Foundation. Open to teams from St Vincent's Hospital Sydney, the Garvan Institute of Medical Research, and the Victor Chang Cardiac Research Institute — programs aligned with the Foundation's discovery and innovation priorities.
The path to pitch day
Challenger Summit returns in May 2027. Application and shortlist dates will be announced here and shared with the Proto Axiom Connect community.
Eligibility & criteria
We make the answer easy. The Proto Axiom Challenger Summit stream is broad by design — we'd rather see one ambitious application than miss it because you weren't sure. The St Vincent's stream has institution-specific eligibility outlined on the partner site.
2026 cohort
Challenger Pitch for Health 2026 was held in Sydney in March 2026 — co-hosted by Proto Axiom and St Vincent's Curran Foundation, Australia's largest medical pitch day. Four programs were recognised across the two streams, and 14 finalists pitched live to a room of 300+ researchers, clinicians, investors and policymakers.
Bowel Disorder Treatment at Home: a home-based system that brings a proven therapy from the clinic into the home, helping people manage chronic bowel conditions.
A first-in-class therapy for heart failure with preserved ejection fraction — a common and fast-growing condition with no treatment that can slow or stop the underlying disease.
A simple, fast and accurate DNA blood test for advanced prostate cancer to detect treatment failure early and enable personalised treatment.
Solving the unmet need for a diagnostic test for rare but devastating genetic diseases — simplifying an accurate lab test into a quick procedure using a small blood sample.
Source: Women's Health Foundry impact dashboard · full finalist list and program detail.
Co-hosts & partners
Supporting partners listed alongside. Add or remove tiles to match the 2027 partner roster.
Take the next step
Join Proto Axiom Connect to be the first to know when the 2027 application form opens — plus program updates, finalist briefings and event invites before they go public. No spam, never shared.
FAQ
Eight starters below. Anything else, the team is one email away.