i Portfolio 8 companies

Scientific breakthroughs, translated.

8 Australian biotech companies — 5 of them formed with Proto Axiom as founding investor. Sourced from 6 universities and the public health system. 4 are approaching clinical trials.

  • 8Companies built
  • 6Universities
  • 4Approaching clinical
  • A$45MDeployed
  • 2021–26Active vintage
Sector Relationship
Showing  8 of 8 companies Founding-investor first · year founded ascending
01 / 08 Founding
Therapeutics

Endo Axiom

A first‑in‑class oral insulin platform using liver‑targeting nanotechnology, addressing a multi‑billion‑dollar diabetes market with no currently approved oral product.

Created with Proto Axiom Approaching clinical
Founded
2023
Origin
University of Sydney / ANZAC Research Institute
Stage
Pre-clinical · IND‑enabling
Modality
Oral insulin · Nanotechnology
Read the full company brief
01 · Endo Axiom

“Insulin in a pill, ten years from bench to first-in-human.”

Oral insulin · Nanotechnology 2023
02 / 08 Founding
Diagnostics

SWAN Genomics

A deep‑tech genomics company developing a next‑generation DNA sequencing platform based on plasmonic nanoantenna technology — true single‑molecule sequencing without the traditional trade‑offs between accuracy, read length, cost and speed.

Created with Proto Axiom
Founded
2023
Origin
UNSW Sydney
Stage
Platform · Series A in market
Modality
Plasmonic nanoantenna · DNA sequencing
Read the full company brief
02 · SWAN Genomics

“A new way to read the molecule. Built in Sydney.”

Plasmonic nanoantenna · DNA sequencing 2023
03 / 08 Founding
Therapeutics

Onyx Axiom

A next‑generation topical antifungal for onychomycosis — combining the safety of topical therapy with efficacy approaching oral drugs, via a novel lyotropic liquid crystal drug‑delivery system.

Created with Proto Axiom Approaching clinical
Founded
2025
Origin
Melbourne
Stage
Clinical · Phase IIb
Modality
Topical antifungal · Lyotropic liquid crystal drug delivery
Read the full company brief
03 · Onyx Axiom

“Phase IIb under way. Topical efficacy, oral-grade results.”

Topical antifungal · Lyotropic liquid crystal drug delivery 2025
04 / 08 Founding
Fertility · Women's health

JumpStart Fertility

A platform biotechnology company developing NAD+ technologies to modulate cellular energy, metabolism and ageing biology — with IVF laboratory media as the lead clinical and commercial application.

Created with Proto Axiom Approaching clinical
Founded
2025
Origin
UNSW · Re‑domiciled from United States
Stage
Clinical · Sibling-embryo trials in preparation
Modality
NAD+ platform · IVF media
Read the full company brief
04 · JumpStart Fertility

“Better embryos, by way of cellular energy.”

NAD+ platform · IVF media 2025
05 / 08 Founding
Bioprocessing · Women's health

Flo Axiom

A bioprocessing technology company developing novel downstream purification materials and workflows that improve the efficiency, cost and scalability of biologics manufacturing.

Created with Proto Axiom
Founded
2026
Origin
Griffith University
Stage
Pre-clinical · Benchmarking & validation
Modality
Downstream purification · Biologics manufacturing
Read the full company brief
05 · Flo Axiom

“A bottleneck in biologics, addressed onshore.”

Downstream purification · Biologics manufacturing 2026
06 / 08 Venture
Cell therapy · Therapeutics

AdvanCell

Clinical‑stage radiopharmaceutical company developing targeted alpha therapies using lead‑212 (²¹²Pb) for cancers with poor existing standards of care.

Venture stake Approaching clinical
Founded
2024
Origin
Sydney, Australia
Stage
Clinical · Phase 2 expansion
Modality
Radiopharmaceuticals · Targeted alpha therapy
Read the full company brief
06 · AdvanCell

“80% PSA50 response. ESMO 2025.”

Radiopharmaceuticals · Targeted alpha therapy 2024
07 / 08 Venture
Therapeutics

Herikin

A desktop RNA printer enabling rapid, distributed production of RNA for research and rare‑disease therapeutic applications.

Venture stake
Founded
2024
Origin
Monash University
Stage
MVP development
Modality
RNA printing · Rare disease therapeutics
Read the full company brief
07 · Herikin

“RNA, on demand, at the bench.”

RNA printing · Rare disease therapeutics 2024
08 / 08 Venture
Cell therapy · Bioprocessing

Cellutech

A novel biomanufacturing platform — initially focused on human‑health compounds, now leading with an AI soil‑microbe product to reduce reliance on imported fertilisers.

Venture stake
Founded
2024
Origin
UNSW Sydney · B10x cohort
Stage
Pilot field trials
Modality
AI soil‑microbe platform
Read the full company brief
08 · Cellutech

“Sovereign fertiliser, made by microbes.”

AI soil‑microbe platform 2024
Capital deployment

A$45M committed across the portfolio. Capital is permanent — milestone-gated, recycled into companies as they hit gates.

Sourced with

University of Sydney, UNSW Sydney, Monash University, Griffith University, ANZAC Research Institute, Sydney Local Health District.

Researcher with a translational program?

Apply to Challenger Summit  →